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Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, numerous patients suffered severe allergic reactions and development of SCF-based therapeutics stopped. A research team led by engineers at The University of Texas at Austin has developed a related therapeutic that they say avoids these major allergic reactions while maintaining its therapeutic activity.
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University of Texas at Austin molecular biosciences professor Jason McLellan was selected as a finalist for the 2022 Blavatnik National Awards for Young Scientists.
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Some of the same researchers at The University of Texas at Austin who created a key to all coronavirus vaccines used in the U.S. have made a similar advance against the human metapneumovirus (hMPV), one of a handful of remaining respiratory viruses for which there is currently no vaccine.
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Dr. Jason McLellan received the 2022 Edith and Peter O'Donnell Award in Medicine from TAMEST (The Academy of Medicine, Engineering and Science of Texas). His research laid the groundwork for vaccines from Pfizer/BioNTech, Moderna, Johnson & Johnson and Novavax.
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In early 2020, scientists at UT Austin were deep into building a unique facility on the Forty Acres, a turbo-charged, biotech playground with a focus on rapid scientific discovery. The biological foundry, as it was called, was part of a partnership in synthetic biology research between The University of Texas at Austin and the U.S. military. It just so happened that the foundry’s founding came along at the same time as the worst biological event in generations: COVID-19.
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Using the same approach they recently used to create effective vaccine candidates against COVID-19 and respiratory syncytial virus (RSV), scientists are tackling another virus: the tick-borne Crimean-Congo hemorrhagic fever (CCHF).
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The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to six faculty members at The University of Texas at Austin. The funding will support ongoing, innovative cancer research at UT and enable advances in immunotherapy, drug development and cancer prevention efforts.
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Imagine biological and chemical imaging tools so advanced that they are able to show the molecular details of a virus as it attaches to and enters cells, or the alignment of vanishingly tiny crystals at an atomic level so as to lend insights for new solar energy technology. New and upcoming additions to UT Austin's Sauer Structural Biology Laboratory are paving the way for just such advances.
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Jason McLellan, a faculty member in the Department of Molecular Biosciences, has been selected as the Texas Inventor of the Year for his role in biomedical research linked to the development of vaccines and treatments for COVID-19.
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The first COVID-19 vaccines were approved for the general public last December, but several months later, most of the world’s population still hasn’t received an injection.
